Combined effect of low-frequency ultrasound and iontophoresis: Applications for transdermal heparin delivery

被引：62

作者：

Le, L

Kost, J

Mitragotri, S

机构：

[1] Univ Calif Santa Barbara, Dept Chem Engn, Santa Barbara, CA 93106 USA

[2] Univ Alabama, Sch Med, Birmingham, AL 35294 USA

[3] Ben Gurion Univ Negev, Dept Chem Engn, IL-84105 Beer Sheva, Israel

[4] Sontra Med Inc, Cambridge, MA 02139 USA

来源：

PHARMACEUTICAL RESEARCH | 2000年 / 17卷 / 09期

关键词：

sonophoresis; synergistic; penetration enhancer; non-invasive;

D O I：

10.1023/A:1026426317413

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：1151 / 1154

页数：4

共 18 条

[1] SONOPHORESIS .2. EXAMINATION OF THE MECHANISM(S) OF ULTRASOUND-ENHANCED TRANSDERMAL DRUG DELIVERY [J].

BOMMANNAN, D ;

MENON, GK ;

OKUYAMA, H ;

ELIAS, PM ;

GUY, RH .

PHARMACEUTICAL RESEARCH, 1992, 9 (08) :1043-1047

[2] SONOPHORESIS .1. THE USE OF HIGH-FREQUENCY ULTRASOUND TO ENHANCE TRANSDERMAL DRUG DELIVERY [J].

BOMMANNAN, D ;

OKUYAMA, H ;

STAUFFER, P ;

GUY, RH .

PHARMACEUTICAL RESEARCH, 1992, 9 (04) :559-564

[3] EFFECT OF ELECTROPORATION ON TRANSDERMAL IONTOPHORETIC DELIVERY OF LUTEINIZING-HORMONE-RELEASING HORMONE (LHRH) IN-VITRO [J].

BOMMANNAN, DB ;

TAMADA, J ;

LEUNG, L ;

POTTS, RO .

PHARMACEUTICAL RESEARCH, 1994, 11 (12) :1809-1814

[4]

GREEN PG, 1993, PHARM SKIN PENETRATI, P311

[5]

Johnson M.E., 1996, THESIS MIT CAMBRIDGE

[6] Synergistic effects of chemical enhancers and therapeutic ultrasound on transdermal drug delivery [J].

Johnson, ME ;

Mitragotri, S ;

Patel, A ;

Blankschtein, D ;

Langer, R .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1996, 85 (07) :670-679

[7] Interaction between penetration enhancers and iontophoresis: Effect on human skin impedance in vivo [J].

Kalia, YN ;

Guy, RH .

JOURNAL OF CONTROLLED RELEASE, 1997, 44 (01) :33-42

[8] Synergistic effect of electric field and ultrasound on transdermal transport [J].

Kost, J ;

Pliquett, U ;

Mitragotri, S ;

Yamamoto, A ;

Langer, R ;

Weaver, J .

PHARMACEUTICAL RESEARCH, 1996, 13 (04) :633-638

[9]

Kost J., 1989, PERCUTANEOUS ABSORPT, P595

[10] ULTRASOUND-MEDIATED TRANSDERMAL PROTEIN DELIVERY [J].

MITRAGOTRI, S ;

BLANKSCHTEIN, D ;

LANGER, R .

SCIENCE, 1995, 269 (5225) :850-853

← 1 2 →