A novel synthesis of new antineoplastic 2'-deoxy-2'-substituted-4'-thiocytidines

被引：92

作者：

Yoshimura, Y

Kitano, K

Satoh, H

Watanabe, M

Miura, S

Sakata, S

Sasaki, T

Matsuda, A

机构：

[1] KANAZAWA UNIV,CANC RES INST,KANAZAWA,ISHIKAWA 920,JAPAN

[2] HOKKAIDO UNIV,FAC PHARMACEUT SCI,SAPPORO,HOKKAIDO 060,JAPAN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1996年 / 61卷 / 03期

关键词：

D O I：

10.1021/jo9519423

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

页码：822 / 823

页数：2

共 24 条

[1] METHYL 3,4-DI-O-ACETYL-2-DEOXY-2(R)-[1H,3H-2,4-DIOXO-1-PYRIMIDINYL]-2-FLUORO-BETA-D-ARABINOPYRANOSIDE - NOVEL NUCLEOSIDE ANALOGS VIA CONDENSATION OF GEM-2,2-DIFLUORO METHYL GLYCOSIDES WITH SILYLATED HETEROCYCLIC BASES [J].

AN, SH ;

BOBEK, M .

TETRAHEDRON LETTERS, 1986, 27 (28) :3219-3222

[2] SYNTHESIS OF ENANTIOMERICALLY PURE (2'R,5'S)-(-)-1-[2-(HYDROXYMETHYL)OXATHIOLAN-5-YL]CYTOSINE AS A POTENT ANTIVIRAL AGENT AGAINST HEPATITIS-B VIRUS (HBV) AND HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) [J].

BEACH, JW ;

JEONG, LS ;

ALVES, AJ ;

POHL, D ;

KIM, HO ;

CHANG, CN ;

DOONG, SL ;

SCHINAZI, RF ;

CHENG, YC ;

CHU, CK .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (08) :2217-2219

[3]

BITONTI AJ, 1994, CANCER RES, V54, P1485

[4] SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 5-FLUORO-4'-THIOURIDINE AND SOME RELATED NUCLEOSIDES [J].

BOBEK, M ;

BLOCH, A ;

PARTHASARATHY, R ;

WHISTLER, RL .

JOURNAL OF MEDICINAL CHEMISTRY, 1975, 18 (08) :784-787

[5] (-)-2'-DEOXY-3'-THIACYTIDINE IS A POTENT, HIGHLY SELECTIVE INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 AND TYPE-2 REPLICATION INVITRO [J].

COATES, JAV ;

CAMMACK, N ;

JENKINSON, HJ ;

JOWETT, AJ ;

JOWETT, MI ;

PEARSON, BA ;

PENN, CR ;

ROUSE, PL ;

VINER, KC ;

CAMERON, JM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1992, 36 (04) :733-739

[6] INHIBITION OF THE REPLICATION OF HEPATITIS-B VIRUS INVITRO BY 2',3'-DIDEOXY-3'-THIACYTIDINE AND RELATED ANALOGS [J].

DOONG, SL ;

TSAI, CH ;

SCHINAZI, RF ;

LIOTTA, DC ;

CHENG, YC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (19) :8495-8499

[7] THE SYNTHESIS AND ANTIVIRAL ACTIVITY OF SOME 4'-THIO-2'-DEOXY NUCLEOSIDE ANALOGS [J].

DYSON, MR ;

COE, PL ;

WALKER, RT .

JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (09) :2782-2786

[8]

HERTEL LW, 1990, CANCER RES, V50, P4417

[9] SYNTHESIS OF 2-DEOXY-2,2-DIFLUORO-D-RIBOSE AND 2-DEOXY-2,2-DIFLUORO-D-RIBOFURANOSYL NUCLEOSIDES [J].

HERTEL, LW ;

KROIN, JS ;

MISNER, JW ;

TUSTIN, JM .

JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (11) :2406-2409

[10]

JENG LS, 1994, TETRAHEDRON LETT, V35, P7573

← 1 2 3 →