Designed evolution of artificial metalloenzymes: protein catalysts made to order

被引：46

作者：

Creus, Marc

Ward, Thomas R.

机构：

[1] Univ Neuchatel, Dept Chem, CH-2009 Neuchatel, Switzerland

[2] Univ Neuchatel, Dept Cellular & Mol Biol, CH-2009 Neuchatel, Switzerland

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2007年 / 5卷 / 12期

关键词：

D O I：

10.1039/b702068f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Artificial metalloenzymes based on biotin-streptavidin technology, a "fusion" of chemistry and biology, illustrate how asymmetric catalysts can be improved and evolved using chemogenetic approaches.

引用

页码：1835 / 1844

页数：10

共 105 条

[1] ASYMMETRIC CATALYST [J].

AKABORI, S ;

SAKURAI, S ;

IZUMI, Y ;

FUJII, Y .

NATURE, 1956, 178 (4528) :323-324

[2] A TAT-streptavidin fusion protein directs uptake of biotinylated cargo into mammalian cells [J].

Albarran, B ;

To, R ;

Stayton, PS .

PROTEIN ENGINEERING DESIGN & SELECTION, 2005, 18 (03) :147-152

[3] Directed evolution of new catalytic activity using the α/β-barrel scaffold (Retraction of vol 403, pg 617, 2000) [J].

Altamirano, MM ;

Blackburn, JM ;

Aguayo, C ;

Fersht, AR .

NATURE, 2002, 417 (6887) :468-468

[4]

[Anonymous], 2002, DIRECTED MOL EVOLUTI

[5] Seventh report of the committee on contact catalysis enzyme catalysts [J].

Armstrong, EF ;

Hilditch, TP .

JOURNAL OF PHYSICAL CHEMISTRY, 1929, 33 :1441-1455

[6] Fancy footwork in the sequence space shuffle [J].

Arnold, FH .

NATURE BIOTECHNOLOGY, 2006, 24 (03) :328-330

[7] Combinatorial and computational challenges for biocatalyst design [J].

Arnold, FH .

NATURE, 2001, 409 (6817) :253-257

[8]

BAYER EA, 1990, METHOD ENZYMOL, V184, P80

[9] A perspective on enzyme catalysis [J].

Benkovic, SJ ;

Hammes-Schiffer, S .

SCIENCE, 2003, 301 (5637) :1196-1202

[10]

Berkessel A, 2005, ASYMMETRIC ORGANOCATALYSIS: FROM BIOMIMETIC CONCEPTS TO APPLICATIONS IN ASYMMETRIC SYNTHESIS, P1, DOI 10.1002/3527604677

← 1 2 3 4 5 6 7 8 9 10 →