Copper-Catalyzed Intermolecular Amination of Acidic Aryl C-H Bonds with Primary Aromatic Amines

被引：134

作者：

Zhao, Huaiqing ^{[1
,2
]}

Wang, Min ^{[1
]}

Su, Weiping ^{[1
]}

Hong, Maochun ^{[1
]}

机构：

[1] Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Fuzhou 350002, Fujian, Peoples R China

[2] Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2010年 / 352卷 / 08期

关键词：

amination; aromatic amines; C-N bond formation; copper catalysis; DIRECT ARYLATION; EFFICIENT SYNTHESIS; AMIDATION; ELECTRON; FUNCTIONALIZATION; AZIRIDINATION; PORPHYRINS; ALKENES; HALIDES; ESTERS;

D O I：

10.1002/adsc.200900856

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A copper-catalyzed intermolecular aerobic oxidative C-H bond amination of various poly-fluorobenzenes with an array of primary aromatic amines was achieved for the first time. The reactivity of the polyfluorobenzenes was observed to depend on the acidity of C-H bonds. Under similar reaction conditions, the C-H bond amination of azoles also occurred.

引用

页码：1301 / 1306

页数：6

共 67 条

[1] A warning on the use of radical traps as a test for radical mechanisms:: They react with palladium hydrido complexes [J].