A vestigial X open reading frame in duck hepatitis B virus

被引：9

作者：

Lin, B ^{[1
]}

Anderson, DA ^{[1
]}

机构：

[1] Maefarlane Burnet Ctr Med Res, Hepatitis Res Unit, Fairfield, Vic 3078, Australia

来源：

INTERVIROLOGY | 2000年 / 43卷 / 03期

关键词：

hepadnaviruses; duck hepatitis B virus; X gene;

D O I：

10.1159/000025037

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Duck hepatitis B virus (DHBV) appears to lack a homologue of the X protein found in mammalian hepadnaviruses. By replacing stop codons in the corresponding region of the DHBV genome, a hypothetical protein which closely matches the hydrophilicity profile of X proteins can be predicted, despite limited sequence homology. We conclude that a full-length X protein was once a common feature of the hepadnaviruses, conserved in structure bur not sequence. Copyright (C) 2000 S. Karger AG, Basel.

引用

页码：185 / 190

页数：6

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