Order and disorder in bacterial genomes

被引：73

作者：

Rocha, EPC ^{[1
]}

机构：

[1] Inst Pasteur, Unite Genet Genomes Bacteriens, F-75724 Paris 15, France

来源：

CURRENT OPINION IN MICROBIOLOGY | 2004年 / 7卷 / 05期

关键词：

D O I：

10.1016/j.mib.2004.08.006

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The availability of sequenced bacterial genomes allows a deeper understanding of their organizational features that are related with fundamental cellular processes such as coordinated gene expression, chromosome replication and cell division. Nevertheless, recent genome comparisons and experimental work highlighted the fluidity of bacterial chromosomes, including genome rearrangements that imperil the selective features of chromosome order. As a result, the clash between elements generating rearrangements and chromosome organization is a classic case of evolutionary conflict.

引用

页码：519 / 527

页数：9

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