Human Infection with a Triple-Reassortant Swine Influenza A(H1N1) Virus Containing the Hemagglutinin and Neuraminidase Genes of Seasonal Influenza Virus

被引：34

作者：

Bastien, Nathalie ^{[1
]}

Antonishyn, Nick A. ^{[3
]}

Brandt, Ken ^{[3
]}

Wong, Christine E. ^{[3
]}

Chokani, Khami ^{[4
]}

Vegh, Niki ^{[3
]}

Horsman, Greg B. ^{[3
]}

Tyler, Shaun ^{[1
]}

Graham, Morag R. ^{[1
,2
]}

Plummer, Frank A. ^{[1
,2
]}

Levett, Paul N. ^{[3
]}

Li, Yan ^{[1
,2
]}

机构：

[1] Publ Hlth Agcy Canada, Natl Microbiol Lab, Winnipeg, MB R3E 3R2, Canada

[2] Univ Manitoba, Dept Med Microbiol, Winnipeg, MB, Canada

[3] Saskatchewan Dis Control Lab, Regina, SK, Canada

[4] Prince Albert Parkland Hlth Reg, Prince Albert, SK, Canada

来源：

JOURNAL OF INFECTIOUS DISEASES | 2010年 / 201卷 / 08期

关键词：

A VIRUSES; H1N1; CANADA; PIGS;

D O I：

10.1086/651507

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A reassortant influenza A(H1N1) virus of swine origin distinct from the pandemic H1N1 2009 strain was isolated from 3 patients, all of whom worked at the same large hog operation in Saskatchewan, Canada. The genomic composition of the isolates has not been previously reported, to our knowledge, and was the product of a genetic reassortment between seasonal H1N1 and triple-reassortant influenza virus that emerged in North American swine during the late 1990s. The neuraminidase and hemagglutinin genes of A/Saskatchewan/5350/2009, A/Saskatchewan/5351/2009, and A/Saskatchewan/5131/2009 were derived from human H1N1 virus and were closely related to those of A/Brisbane/59/2007.

引用

页码：1178 / 1182

页数：5

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