The spoIIE locus is involved in the Spo0A-dependent switch in the location of FtsZ rings in Bacillus subtilis

被引：53

作者：

Khvorova, A ^{[1
]}

Zhang, L ^{[1
]}

Higgins, ML ^{[1
]}

Piggot, PJ ^{[1
]}

机构：

[1] Temple Univ, Sch Med, Dept Microbiol & Immunol, Philadelphia, PA 19140 USA

来源：

JOURNAL OF BACTERIOLOGY | 1998年 / 180卷 / 05期

关键词：

D O I：

10.1128/JB.180.5.1256-1260.1998

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A switch in the location of FtsZ ring structures from medial to polar is one of the earliest morphological indicators of sporulation in Bacillus subtilis. This switch can be artificially caused during vegetative growth by induction of an active form, Sad67, of the transcription regulator, Spo0A (P. A. Levin and R. Losick, Genes Dev. 10:478-488, 1996). We have used immunofluorescence microscopy to show that the switch in FtsZ ring location during vegetative growth caused by Sad67 induction is blocked by a spoIIE deletion mutation. The spoIIE mutation also impaired polar FtsZ ring formation during sporulation. These results suggest that SpoIIE mediates the Spo0A-directed formation of polar FtsZ rings.

引用

页码：1256 / 1260

页数：5

共 32 条

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