The role of the immune system in the initiation and persistence of the Euprymna scolopes-Vibrio fischeri symbiosis

被引:75
作者
McFall-Ngai, Margaret [1 ]
Nyholm, Spencer V. [2 ]
Castillo, Maria G. [3 ]
机构
[1] Univ Wisconsin, Dept Med Microbiol & Immunol, Madison, WI 53706 USA
[2] Univ Connecticut, Dept Mol & Cell Biol, Storrs, CT 06269 USA
[3] New Mexico State Univ, Dept Biol, Las Cruces, NM 88003 USA
基金
美国国家科学基金会;
关键词
Euprymna; Vibrio fischeri; Hemocytes; MAMP; PRR; Symbiosis; Complement; ANIMAL-BACTERIAL ASSOCIATION; LIGHT-ORGAN; HOST SQUID; MORPHOGENESIS; COLONIZATION; GENES; DIVERSIFICATION; PEROXIDASE; INDUCTION; MUTUALISM;
D O I
10.1016/j.smim.2009.11.003
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The squid-vibrio symbiosis is an experimental system being studied as a model of the chronic colonization of animal epithelia by bacterial partners. One principal question being asked with this model is: what is the role of the immune system in the dynamics of the onset and maintenance of the symbiotic state? This review focuses upon results of research to date, which have demonstrated that both cell-mediated and cell-free components of the innate immune system are involved in these processes. (C) 2009 Published by Elsevier Ltd.
引用
收藏
页码:48 / 53
页数:6
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