Human milk contains S100B protein

被引：29

作者：

Gazzolo, D

Monego, G

Corvino, V

Bruschettini, M

Bruschettini, P

Zelano, G

Michetti, F

机构：

[1] Univ Sacred Heart, Inst Anat, I-00168 Rome, Italy

[2] Giannina Gaslini Childrens Univ Hosp, Dept Pediat, I-16147 Genoa, Italy

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS | 2003年 / 1619卷 / 02期

关键词：

S100B protein; newborn; human milk;

D O I：

10.1016/S0304-4165(02)00499-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The present study constitutes the first finding of the calcium-binding protein S100B and of its mRNA in human milk, as revealed by a quantitative immunoluminometric assay, by Western blot analysis and by reverse transcription-polymerase chain reaction (RT-PCR) assay followed by restriction enzyme digestion. The concentration of S100B in milk is markedly higher than that observed in other biological fluids such as cord blood, peripheral blood, urine, cerebrospinal fluid and amniotic fluid. This finding could be related to a possible trophic role, which has been hypothesized for the protein. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：209 / 212

页数：4

共 20 条

[1] Brainstem maturation in premature infants as a function of enteral feeding type [J].