Treatment of insomnia by concomitant therapy with Zopiclone and Aniracetam in patients with cerebral infarction, cerebroatrophy, Alzheimer's disease and Parkinson's disease

被引：24

作者：

Katsunuma, H

Shimizu, T

Ogawa, K

Kubo, H

Ishida, H

Yoshihama, A

机构：

[1] Omotemachi Hosp, Tachikawa Med Ctr, Dept Internal Med, Nagoya, Aichi, Japan

[2] Omotemachi Hosp, Tachikawa Med Ctr, Dept Radiol, Nagoya, Aichi, Japan

[3] Kashiwazaki Kosai Hosp, Kashiwazaki, Japan

来源：

PSYCHIATRY AND CLINICAL NEUROSCIENCES | 1998年 / 52卷 / 02期

关键词：

aged; Alzheimer's disease; Aniracetam; cerebral infarction; cerebroatrophy; Parkinson's disease; Zopiclone;

D O I：

10.1111/j.1440-1819.1998.tb01028.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

For insomniac patients, sleeping drugs are used; in addition, concomitant therapy with other drugs has been tried in an effort to prevent a decrease in the effects due to long-term continuous use. This report presents the results of a study on the sleeping effects in nine aged patients with insomnia associated with cerebrovascular and non-cerebrovascular disorders who received concomitant therapy with Zopiclone and Aniracetam. The treatment in 7/9 cases (78%) was found to be effective, showing more than 50% prolongation of sleeping time, and in two casts (22%) was found to be ineffective. We discuss the mechanism of action referring to the literature.

引用

页码：198 / 200

页数：3

共 5 条

[1]

HIROSE N, 1993, JPN PHARMACOL THER, V21, P2361

[2]

IIDA H, 1994, J NUCL MED, V35, P2019

[3] ZOPICLONE VERSUS NITRAZEPAM - A DOUBLE-BLIND COMPARATIVE-STUDY OF EFFICACY AND TOLERANCE IN ELDERLY PATIENTS WITH CHRONIC INSOMNIA [J].