Escherichia coli acid resistance:: Tales of an amateur acidophile

被引:695
作者
Foster, JW [1 ]
机构
[1] Univ S Alabama, Coll Med, Dept Microbiol & Immunol, Mobile, AL 36695 USA
关键词
D O I
10.1038/nrmicro1021
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Gastrointestinal pathogens are faced with an extremely acidic environment. Within moments, a pathogen such as Escherichia coli O157:H7 can move from the nurturing pH 7 environment of a hamburger to the harsh pH 2 milieu of the stomach. Surprisingly, certain microorganisms that grow at neutral pH have elegantly regulated systems that enable survival during excursions into acidic environments. The best-characterized acid-resistance system is found in E. coli.
引用
收藏
页码:898 / 907
页数:10
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