Escherichia coli acid resistance:: Tales of an amateur acidophile

被引：695

作者：

Foster, JW ^{[1
]}

机构：

[1] Univ S Alabama, Coll Med, Dept Microbiol & Immunol, Mobile, AL 36695 USA

来源：

NATURE REVIEWS MICROBIOLOGY | 2004年 / 2卷 / 11期

关键词：

D O I：

10.1038/nrmicro1021

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Gastrointestinal pathogens are faced with an extremely acidic environment. Within moments, a pathogen such as Escherichia coli O157:H7 can move from the nurturing pH 7 environment of a hamburger to the harsh pH 2 milieu of the stomach. Surprisingly, certain microorganisms that grow at neutral pH have elegantly regulated systems that enable survival during excursions into acidic environments. The best-characterized acid-resistance system is found in E. coli.

引用

页码：898 / 907

页数：10

共 73 条

[31] Green fluorescent protein as a noninvasive intracellular pH indicator [J].

Kneen, M ;

Farinas, J ;

Li, YX ;

Verkman, AS .

BIOPHYSICAL JOURNAL, 1998, 74 (03) :1591-1599

[32] THE CELLULAR CONCENTRATION OF THE SIGMA(S) SUBUNIT OF RNA-POLYMERASE IN ESCHERICHIA-COLI IS CONTROLLED AT THE LEVELS OF TRANSCRIPTION TRANSLATION, AND PROTEIN STABILITY [J].

LANGE, R ;

HENGGEARONIS, R .

GENES & DEVELOPMENT, 1994, 8 (13) :1600-1612

[33] Mechanisms of acid resistance in enterohemorrhagic Escherichia coli [J].

Lin, JS ;

Smith, MP ;

Chapin, KC ;

Baik, HS ;

Bennett, GN ;

Foster, JW .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1996, 62 (09) :3094-3100

[34] COMPARATIVE-ANALYSIS OF EXTREME ACID SURVIVAL IN SALMONELLA-TYPHIMURIUM, SHIGELLA-FLEXNERI, AND ESCHERICHIA-COLI [J].

LIN, JS ;

LEE, IS ;

FREY, J ;

SLONCZEWSKI, JL ;

FOSTER, JW .

JOURNAL OF BACTERIOLOGY, 1995, 177 (14) :4097-4104

[35] pH-dependent modulation of cyclic AMP levels and GadW-dependent repression of RpoS affect synthesis of the GadX regulator and Escherichia coli acid resistance [J].

Ma, Z ;

Richard, H ;

Foster, JW .

JOURNAL OF BACTERIOLOGY, 2003, 185 (23) :6852-6859

[36] GadE (YhiE) activates glutamate decarboxylase-dependent acid resistance in Escherichia coli K-12 [J].

Ma, Z ;

Gong, SM ;

Richard, H ;

Tucker, DL ;

Conway, T ;

Foster, JW .

MOLECULAR MICROBIOLOGY, 2003, 49 (05) :1309-1320

[37] Collaborative regulation of Escherichia coli glutamate-dependent acid resistance by two AraC-like regulators, GadX and GadW (YhiW) [J].

Ma, Z ;

Richard, H ;

Tucker, DL ;

Conway, T ;

Foster, JW .

JOURNAL OF BACTERIOLOGY, 2002, 184 (24) :7001-7012

[38]

MA Z, IN PRESS J BACTERIOL

[39] The promoter of the operon encoding the F0F1 ATPase of Streptococcus pneumoniae is inducible by pH [J].

Martín-Galiano, AJ ;

Ferrándiz, MJ ;

de la Campa, AG .

MOLECULAR MICROBIOLOGY, 2001, 41 (06) :1327-1338

[40] Regulatory network of acid resistance genes in Escherichia coli [J].

Masuda, N ;

Church, GM .

MOLECULAR MICROBIOLOGY, 2003, 48 (03) :699-712

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