Synthesis of both enantiomers of trans 3-hydroxypipecolic acid.

被引：51

作者：

Greck, C

Ferreira, F

Genet, JP

机构：

[1] Lab. de Synthèse Organique, Associé au CNRS, Ecl. Natl. Sup. de Chimie de Paris, 75231 Paris Cédex 05, 11, rue Pierre et Marie Curie

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 12期

关键词：

D O I：

10.1016/0040-4039(96)00191-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first syntheses of enantiomerically pure (2R, 3R) and (2S, 3S) 3-hydroxypipecolic acids 1 and 2 respectively, have been achieved from methyl 7-methyl-3-oxo-6-octenoate. Key steps involved asymmetric hydrogenation and electrophilic amination.

引用

页码：2031 / 2034

页数：4

共 19 条

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