Stiff-leg syndrome:: A focal form of stiff-man syndrome

被引：54

作者：

Saiz, A ^{[1
]}

Graus, F ^{[1
]}

Valldeoriola, F ^{[1
]}

Valls-Solé, J ^{[1
]}

Tolosa, E ^{[1
]}

机构：

[1] Univ Barcelona, Hosp Clin & Prov, Dept Med, Neurol Serv, E-08036 Barcelona, Spain

来源：

ANNALS OF NEUROLOGY | 1998年 / 43卷 / 03期

关键词：

D O I：

10.1002/ana.410430322

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report on 2 patients who presented stiffness and spasms similar to those of stiff-man syndrome (SMS) that were limited to one leg for up to 11 years. Patients had serum glutamic acid decarboxylase (GAD) autoantibodies in high titer, clinical evidence of organ-specific autoimmunity, and electromyographic pattern of continuous motor unit activity with abnormally enhanced exteroceptive reflexes. The clinical and immunological profile suggests that this disorder may be a focal form of SMS.

引用

页码：400 / 403

页数：4

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