Kinetics and significance of serum hepatitis C virus core antigen in patients with acute hepatitis C

被引：20

作者：

Cividini, A

Cerino, A

Muzzi, A

Furione, M

Rebucci, C

Segagni, L

Gatti, M

Barnaba, V

Mondelli, MU

机构：

[1] IRCCS, Policlin San Matteo, Lab Ricerca Area Infettivol, I-27100 Pavia, Italy

[2] IRCCS, Policlin San Matteo, Dipartimento Malattie Infett, I-27100 Pavia, Italy

[3] IRCCS, Policlin San Matteo, Serv Virol, I-27100 Pavia, Italy

[4] Univ Pavia, I-27100 Pavia, Italy

[5] Univ Roma La Sapienza, Policlin Umberto I, Fdn A Cesalpino, Lab Immunol Cellulare & Mol, Rome, Italy

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2003年 / 41卷 / 05期

关键词：

D O I：

10.1128/JCM.41.5.2144-2146.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

An immunoassay detecting hepatitis C virus core antigen was evaluated for its ability to predict clinical outcome in a series of patients with acute hepatitis C. In subjects who cleared the virus, core antigen was no longer detectable within 16 weeks of onset, whereas considerable fluctuations were noted among patients progressing to chronic hepatitis, one of whom showed consistently negative values despite the intermittent presence of viral RNA.

引用

页码：2144 / 2146

页数：3

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