Labeling of organic biomolecules with ethynylferrocene

被引:45
作者
Coutouli-Argyropoulou, E [1 ]
Tsitabani, M
Petrantonakis, G
Terzis, A
Raptopoulou, C
机构
[1] Aristotle Univ Thessaloniki, Dept Chem, Thessaloniki 54124, Greece
[2] NCSR Demokritos, Inst Mat Sci, Aghia Paraskevi 15310, Attiki, Greece
关键词
D O I
10.1039/b300191a
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The Sonogashira coupling reaction of ethynylferrocene with adenine, uracil, tyrosine and steroid derivatives was studied; with the exception of tyrosine it was proved to be a good route for the attachment of ferrocene to these representative biomolecules. In addition the transformation of alkynyl uracil to furanopyrimidone derivatives was investigated and the formation of the furanopyrimidone ring was confirmed by an X-ray crystallographic analysis carried out on product 16.
引用
收藏
页码:1382 / 1388
页数:7
相关论文
共 65 条
  • [51] Sonogashira K., 1991, COMPREHENSIVE ORGANI, V3, P521, DOI DOI 10.1016/B978-0-08-052349-1.00071-8
  • [52] Electrochemical biosensors:: Recommended definitions and classification
    Thévenot, DR
    Toth, K
    Durst, RA
    Wilson, GS
    [J]. ANALYTICAL LETTERS, 2001, 34 (05) : 635 - 659
  • [53] Thomas KRJ, 2000, ORGANOMETALLICS, V19, P1008
  • [54] PREPARATION OF CARBOALKOXYALKYLPHENYLALANINE DERIVATIVES FROM TYROSINE
    TILLEY, JW
    SARABU, R
    WAGNER, R
    MULKERINS, K
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (03) : 906 - 910
  • [55] Synthesis of methylketone containing nucleoside triphosphates for RNA labelling
    Trévisiol, E
    Defrancq, E
    Lhomme, J
    Laayoun, A
    Cros, P
    [J]. TETRAHEDRON, 2000, 56 (35) : 6501 - 6510
  • [56] Trévisiol E, 2000, EUR J ORG CHEM, V2000, P211
  • [57] Miniaturized biochemical sensing devices based on planar bilayer lipid membranes
    Trojanowicz, M
    [J]. FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY, 2001, 371 (02): : 246 - 260
  • [58] Electrochemical analysis of DNA amplified by the polymerase chain reaction with a ferrocenylated oligonucleotide
    Uto, Y
    Kondo, H
    Abe, M
    Suzuki, T
    Takenaka, S
    [J]. ANALYTICAL BIOCHEMISTRY, 1997, 250 (01) : 122 - 124
  • [59] Wang J, 2001, ELECTROANAL, V13, P983, DOI 10.1002/1521-4109(200108)13:12<983::AID-ELAN983>3.0.CO
  • [60] 2-#