Consistent over-estimation of gene number in complex plant genomes

被引：122

作者：

Bennetzen, JL ^{[1
]}

Coleman, C

Liu, RY

Ma, JX

Ramakrishna, W

机构：

[1] Univ Georgia, Dept Genet, Athens, GA 30602 USA

[2] Brigham Young Univ, Dept Anim & Plant Sci, Provo, UT 84602 USA

[3] Michigan Technol Univ, Dept Biol Sci, Houghton, MI 49931 USA

来源：

CURRENT OPINION IN PLANT BIOLOGY | 2004年 / 7卷 / 06期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/j.pbi.2004.09.003

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The first comprehensive comparison of gene content between higher plant species provided the unexpected conclusions that rice contained about twice as many genes as Arabidopsis, and that about half of the rice genes had no obvious homologs in any other organism. Our subsequent analyses indicate that most of these "extra, novel" rice genes are mis-annotated segments of transposable elements, especially retrotransposons. Aggressive annotation of a randomly selected subset of the rice genome suggests that the gene number is less than 40 000. The five fantasies of automated plant gene discovery are described and a protocol is provided to minimize (or at least predict) the inaccuracy of future plant genome annotations.

引用

页码：732 / 736

页数：5

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