Polarized growth and organelle segregation in yeast: the tracks, motors, and receptors

被引：116

作者：

Bretscher, A ^{[1
]}

机构：

[1] Cornell Univ, Dept Mol Biol & Genet, Ithaca, NY 14853 USA

来源：

JOURNAL OF CELL BIOLOGY | 2003年 / 160卷 / 06期

关键词：

polarity; transport; actin; myosin; vacuole;

D O I：

10.1083/jcb.200301035

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In yeast, growth and organelle segregation requires formin-dependent assembly of polarized actin cables. These tracks are used by myosin Vs to deliver secretory vesicles for cell growth, organelles for their segregation, and mRNA for fate determination. Several specific receptors have been identified that interact with the cargo-binding tails of the myosin Vs. A recent study implicates specific degradation in the bud of the vacuolar receptor, Vac17, as a mechanism for cell cycle-regulated segregation of this organelle.

引用

页码：811 / 816

页数：6

共 76 条

[41] Bim1p/Yeb1p mediates the Kar9p-dependent cortical attachment of cytoplasmic microtubules
Miller, RK
Cheng, SC
Rose, MD
[J]. MOLECULAR BIOLOGY OF THE CELL, 2000, 11 (09) : 2949 - 2959
[42] Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions
Nagashima, K
Torii, S
Yi, ZH
Igarashi, M
Okamoto, K
Takeuchi, T
Izumi, T
[J]. FEBS LETTERS, 2002, 517 (1-3) : 233 - 238
[43] Dynamic localization and function of Bni1p at the sites of directed growth in Saccharomyces cerevisiae
Ozaki-Kuroda, K
Yamamoto, Y
Nohara, H
Kinoshita, M
Fujiwara, T
Irie, K
Takai, Y
[J]. MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (03) : 827 - 839
[44] Establishment of cell polarity in yeast
Pringle, JR
Bi, E
Harkins, HA
Zahner, JE
DeVirgilio, C
Chant, J
Corrado, K
Fares, H
[J]. COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1995, 60 : 729 - 744
[45] Role of formins in actin assembly: Nucleation and barbed-end association
Pruyne, D
Evangelista, M
Yang, CS
Bi, EF
Zigmond, S
Bretscher, A
Boone, C
[J]. SCIENCE, 2002, 297 (5581) : 612 - 615
[46] Pruyne D, 2000, J CELL SCI, V113, P365
[47] Pruyne D, 2000, J CELL SCI, V113, P571
[48] Tropomyosin-containing actin cables direct the Myo2p-dependent polarized delivery of secretory vesicles in budding yeast
Pruyne, DW
Schott, DH
Bretscher, A
[J]. JOURNAL OF CELL BIOLOGY, 1998, 143 (07) : 1931 - 1945
[49] The yeast class V myosins, Myo2p and Myo4p, are nonprocessive actin-based motors
Reck-Peterson, SL
Tyska, MJ
Novick, PJ
Mooseker, MS
[J]. JOURNAL OF CELL BIOLOGY, 2001, 153 (05) : 1121 - 1126
[50] Robinson NCG, 1999, MOL CELL BIOL, V19, P3580

← 1 2 3 4 5 6 7 8 →