Bioorganic chemistry of ceramide

被引：75

作者：

Brodesser, S ^{[1
]}

Sawatzki, P ^{[1
]}

Kolter, T ^{[1
]}

机构：

[1] Univ Bonn, Kekule Inst Organ Chem & Biochem, D-53121 Bonn, Germany

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 2003卷 / 11期

关键词：

bioorganic chemistry; ceramide; cell surface engineering; glycolipids; sphingolipids;

D O I：

10.1002/ejoc.200200518

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ceramide is the hydrophobic membrane anchor of glycosphingolipids, a vital component of the human skin, and a novel signaling substance. We give an overview of ceramide analogues that have been prepared to address biochemical questions related to the various functions of this lipid. We also discuss possible therapeutic applications. (C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).

引用

页码：2021 / 2034

页数：14

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