Update on the genus Malassezia

被引:134
作者
Ashbee, H. R. [1 ]
机构
[1] Gen Infirm, Mycol Reference Ctr, Dept Microbiol, Leeds LS1 3EX, W Yorkshire, England
关键词
Malassezia; atopic eczema/dermatitis syndrome; immune system; FRAGMENT LENGTH POLYMORPHISM; ATOPIC-DERMATITIS PATIENTS; INTENSIVE-CARE-UNIT; HEALTHY-HUMAN SKIN; SEBORRHEIC DERMATITIS; PITYRIASIS-VERSICOLOR; PITYROSPORUM-OVALE; MOLECULAR ANALYSIS; IN-VITRO; ANTIMICROBIAL PEPTIDES;
D O I
10.1080/13693780701191373
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Malassezia yeasts are commensals of normal human skin, but also cause pityriasis versicolor, seborrhoeic dermatitis and evidence is accumulating that they play a significant role in atopic eczema/dermatitis syndrome (AEDS; formerly atopic dermatitis). The taxonomy of the genus has changed considerably and is likely to change more in the future. Our understanding of the interaction between Malassezia and the host demonstrates that it has the paradoxical ability to both stimulate and suppress the immune response directed against it and there is a fine balance in its existence at the interface between commensalism and pathogenicity.
引用
收藏
页码:287 / 303
页数:17
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