Sodium MRI of human articular cartilage in vivo

被引：166

作者：

Reddy, R

Insko, EK

Noyszewski, EA

Dandora, R

Kneeland, JB

Leigh, JS

机构：

[1] Univ Penn, Dept Radiol, Stellar Chance Labs, Philadelphia, PA 19104 USA

[2] Metab Magnet Resonance Res & Comp Ctr, Philadelphia, PA USA

来源：

MAGNETIC RESONANCE IN MEDICINE | 1998年 / 39卷 / 05期

关键词：

MRI; sodium; cartilage; osteoarthritis;

D O I：

10.1002/mrm.1910390505

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Preliminary results from in vivo sodium MRI of human patellar articular cartilage are presented. Sodium images generated of an in vitro bovine patella clearly distinguish the region of proteoglycan depletion from the region of healthy cartilage. This provides the first evidence that sodium imaging may be used to detect changes due to osteoarthritis in vivo, The process of optimizing imaging time acid signal-to-noise ratio, as well as potential implications in the detection of osteoarthritic change, are discussed.

引用

页码：697 / 701

页数：5

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