Absolute stereochemistry of halichlorine; A potent inhibitor of VCAM-1 induction

被引：87

作者：

Arimoto, H

Hayakawa, I

Kuramoto, M

Uemura, D

机构：

[1] Shizuoka Univ, Fac Sci, Dept Chem, Shizuoka 422, Japan

[2] Ehime Univ, Adv Instrumentat Ctr Chem Anal, Matsuyama, Ehime 79077, Japan

[3] Nagoya Univ, Grad Sch Sci, Dept Chem, Chikusa Ku, Nagoya, Aichi 46401, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 08期

关键词：

D O I：

10.1016/S0040-4039(97)10714-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The absolute stereochemistry of a marine alkaloid halichlorine, which significantly inhibits VCAM-1 induction in HUVE cells, was established by synthesis of a degradation product of natural product. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：861 / 862

页数：2

共 4 条

[1] Pinnaic acid and tauropinnaic acid: Two novel fatty acids composing a 6-Azaspiro[4.5]decane unit from the Okinawan bivalve Pinna muricata
Chou, T
Kuramoto, M
Otani, Y
Shikano, M
Yazawa, K
Uemura, D
[J]. TETRAHEDRON LETTERS, 1996, 37 (22) : 3871 - 3874
[2] Halichlorine, an inhibitor of VCAM-1 induction from the marine sponge Halichondria okadai Kadota
Kuramoto, M
Tong, C
Yamada, K
Chiba, T
Hayashi, Y
Uemura, D
[J]. TETRAHEDRON LETTERS, 1996, 37 (22) : 3867 - 3870
[3] TAKANO S, 1994, SYNLETT, P119
[4] YADAV JS, 1988, TETRAHEDRON LETT, V29, P2737

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