Pharmacotherapy in the treatment of male sexual dysfunction

Recent advances in the use of drugs for the treatment of two major sexual dysfunctions in men, erectile dysfunction and premature ejaculation, are presented. Optimal parameters for use, overall efficacy, and actual or presumed mechanism of action are discussed for both oral and nonoral medications that have been commonly used in the past 10 to 15 years. The limitations of the specific pharmacotherapies for treating sexual dysfunction, as well as the limitations of current research investigating various pharmacological options, are acknowledged. General issues surrounding the rising use of drugs for treating sexual dysfunction are also discussed, including the value of considering therapeutic seals and treatment options that focus on more than just restoration of genital function.