Use of nonprohibited hallucinogenic plants:: Increasing relevance for public health?: A case report and literature review on the consumption of Salvia divinorum

被引:46
作者
Bücheler, R
Gleiter, CH
Schwoerer, R
Gaertner, I
机构
[1] Univ Klinikum Tubingen, Abt Klin Pharmakol, D-72076 Tubingen, Germany
[2] Med Dienst Krankenversicherung MDK Baden Wurttemb, D-77933 Lahr, Germany
[3] Univ Klinikum Tubingen, Abt Allgemeine Psychiat & Psychotherapie & Polikl, D-72076 Tubingen, Germany
关键词
D O I
10.1055/s-2005-837763
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Introduction: We want to call attention to a mint plant, called diviner's sage (Salvia divinorum), originally used in shamanic ceremonies of the Mazatec Indians of Mexico. On numerous websites of the internet, this ancient herbal drug and its extracts are offered as a legal means of widening individual awareness. Regarding its dose-response relationship, the active ingredient, salvinorin A, is one of the most potent naturally occurring hallucinogens. Laws on controlled substances, except for Finland, Denmark and Australia, do not prohibit cultivating, consuming or dealing with Salvia divinorum. Ingestion by smoking, vaporising or chewing, induces a short-lived inebriant state with intense, bizarre feelings of depersonalization. This article wants to be a signal for physicians or psychotherapists to take Salvia into consideration, when exploring young people for drug use. Methods: We report the individual perceptions of a young man consuming Salvia divinorum. We review the scarce scientific literature and consider relevant internet websites. Discussion: We define open issues for further investigations and try to discuss why Salvia divinorum may be of interest for teenagers and young adults in Europe.
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页码:1 / 5
页数:5
相关论文
共 42 条
[1]  
*BUND WIESB, 2002, RAUSCHG
[2]   The plant-derived hallucinogen, salvinorin A, produces κ-opioid agonist-like discriminative effects in rhesus monkeys [J].
Butelman, ER ;
Harris, TJ ;
Kreek, MJ .
PSYCHOPHARMACOLOGY, 2004, 172 (02) :220-224
[3]   Salvinorin A, an active component of the hallucinogenic sage Salvia divinorum is a highly efficacious κ-opioid receptor agonist:: Structural and functional considerations [J].
Chavkin, C ;
Sud, S ;
Jin, WZ ;
Stewart, J ;
Zjawiony, JK ;
Siebert, DJ ;
Toth, BA ;
Hufeisen, SJ ;
Roth, BL .
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2004, 308 (03) :1197-1203
[4]   Screening for cannabis use disorders in an adolescent emergency department sample [J].
Chung, T ;
Colby, SM ;
O'Leary, TA ;
Barnett, NP ;
Monti, PM .
DRUG AND ALCOHOL DEPENDENCE, 2003, 70 (02) :177-186
[5]   Role of κ-opioid receptor activation in pharmacological preconditioning of swine [J].
Coles, JA ;
Sigg, DC ;
Iaizzo, PA .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2003, 284 (06) :H2091-H2099
[6]   Testing hypotheses about the relationship between cannabis use and psychosis [J].
Degenhardt, L ;
Hall, W ;
Lynskey, M .
DRUG AND ALCOHOL DEPENDENCE, 2003, 71 (01) :37-48
[7]  
Dinkel M, 2001, NOTARZT, V17, P105, DOI DOI 10.1055/S-2001-14123
[8]   The standardized psychometric assessment of altered states of consciousness (ASCs) in humans [J].
Dittrich, A .
PHARMACOPSYCHIATRY, 1998, 31 :80-84
[9]   Analgesia from a peripherally active κ-opioid receptor agonist in patients with chronic pancreatitis [J].
Eisenach, JC ;
Carpenter, R ;
Curry, R .
PAIN, 2003, 101 (1-2) :89-95
[10]  
EPLING CARL, 1962, BOT MUS LEAFL HARVARD UNIV, V20, P75