The first Au-nanoparticles catalyzed green synthesis of propargylamines via a three-component coupling reaction of aldehyde, alkyne and amine

被引:184
作者
Kidwai, Mazaahir [1 ]
Bansal, Vikas
Kumar, Ajeet
Mozumdar, Subho
机构
[1] Univ Delhi, Dept Chem, Green Chem Res Lab, Delhi 110007, India
[2] Univ Delhi, Dept Chem, Lab Nanobiotechnol, Delhi 110007, India
关键词
D O I
10.1039/b702287e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Recyclable Au-nanoparticles provide an efficient, economic, novel route for multi component A(3) coupling reaction of aldehyde, amine and alkyne. This method provides the wide range of substrate applicability. This protocol avoids the use of heavy metals, co-catalyst and gives the propargylamine in excellent yields.
引用
收藏
页码:742 / 745
页数:4
相关论文
共 46 条
[1]   Multiple-component condensation strategies for combinatorial library synthesis [J].
Armstrong, RW ;
Combs, AP ;
Tempest, PA ;
Brown, SD ;
Keating, TA .
ACCOUNTS OF CHEMICAL RESEARCH, 1996, 29 (03) :123-131
[2]  
Boulton AA, 1997, DRUG DEVELOP RES, V42, P150, DOI 10.1002/(SICI)1098-2299(199711/12)42:3/4<150::AID-DDR6>3.0.CO
[3]  
2-P
[4]   MONODISPERSED COLLOIDAL METAL PARTICLES FROM NONAQUEOUS SOLUTIONS - CATALYTIC BEHAVIOR IN HYDROGENOLYSIS AND ISOMERIZATION OF HYDROCARBONS OF SUPPORTED PLATINUM PARTICLES [J].
BOUTONNET, M ;
KIZLING, J ;
TOUROUDE, R ;
MAIRE, G ;
STENIUS, P .
CATALYSIS LETTERS, 1991, 9 (5-6) :347-354
[5]   THE PREPARATION OF MONODISPERSE COLLOIDAL METAL PARTICLES FROM MICRO-EMULSIONS [J].
BOUTONNET, M ;
KIZLING, J ;
STENIUS, P .
COLLOIDS AND SURFACES, 1982, 5 (03) :209-225
[6]   A titanium-catalyzed three-component coupling to generate α,β-unsaturated β-iminoamines [J].
Cao, CS ;
Shi, YH ;
Odom, AL .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (10) :2880-2881
[7]   Hydroxyapatite supported copper catalyst for effective three-component coupling [J].
Choudary, BM ;
Sridhar, C ;
Kantam, ML ;
Sreedhar, B .
TETRAHEDRON LETTERS, 2004, 45 (39) :7319-7321
[8]  
Domling A., 2000, ANGEW CHEM, V112, P3300
[9]  
Dyker G, 1999, ANGEW CHEM INT EDIT, V38, P1699, DOI 10.1002/(SICI)1521-3773(19990614)38:12<1698::AID-ANIE1698>3.0.CO
[10]  
2-6