Surveillance after colorectal cancer surgery

被引:24
作者
De Salvo, L
Razzetta, F
Arezzo, A
Tassone, U
Bogliolo, G
Bruzzone, D
Mattioli, F
机构
[1] Univ Genoa, Ist Clin Chirurg, Dept Surg, I-16132 Genoa, Italy
[2] Univ Genoa, Dept Internal Med, I-16132 Genoa, Italy
来源
EUROPEAN JOURNAL OF SURGICAL ONCOLOGY | 1997年 / 23卷 / 06期
关键词
colorectal cancer; cancer recurrence; post-operative follow-up;
D O I
10.1016/S0748-7983(97)93045-6
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Early diagnosis of local and distant recurrences of colorectal cancer remains difficult and there is no agreement on the effectiveness of follow-up in these patients, The aim of this study is to assess the value of our method of follow-up. We consider 239 patients with colorectal cancer and at Beast 2 years follow-up following radical resection, PI local recurrence appeared in 26 patients (10.9%), a distant metastasis in 41 (17.1%), while in seven (2.9%) local and distant recurrences appeared simultaneously. Local recurrence was detected because of an increase in carcinoembryonic antigen (CEA) level in 15 patients (57.7%), during a scheduled endoscopy in four (15.4%) and because of symptoms in seven (26.9%), Tn seven patients (26.9%) a radical resection was possible, Distant metastases were detected by CEA levels in 20 patients (48.8%), by ultrasonography (U.S.) in 12 (29.3%) and by chest X-ray in five (12.2%). In 13 of 26 patients with liver metastases a resection was performed. This study shows that few patients benefit from follow-up and only CEA levels and liver U.S. performed intensively between 15 and 36 months after surgery are useful in early detection of recurrences, A modification or the follow-up to the single patient, according to the stage, location and grading of cancer, could improve the results, so lowering the tests of this expensive practice.
引用
收藏
页码:522 / 525
页数:4
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