Tuberculosis vaccines - an update

被引：82

作者：

Andersen, Peter ^{[1
]}

机构：

[1] Statens Serum Inst, Dept Infect Dis Immunol, DK-2300 Copenhagen, Denmark

来源：

NATURE REVIEWS MICROBIOLOGY | 2007年 / 5卷 / 07期

关键词：

D O I：

10.1038/nrmicro1703

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The current tuberculosis (TB) vaccine Mycobacterium bovis bacillus Calmette-Guerin (BCG) is the most widely used vaccine worldwide, but it does not prevent the establishment of latent TB or reactivation of pulmonary disease in adults. Peter Andersen looks at the progress of the candidates to improve or replace BCG.

引用

页码：484 / U16

页数：7

共 17 条

[1] Protective immunity to tuberculosis with Ag85B-ESAT-6 in a synthetic cationic adjuvant system IC31 [J].

Agger, Else Marie ;

Rosenkrands, Ida ;

Olsen, Anja Weinreich ;

Hatch, Graham ;

Williams, Ann ;

Kritsch, Constantia ;

Lingnau, Karen ;

von Gabain, Alexander ;

Andersen, Claire Swetman ;

Korsholm, Karen Smith ;

Andersen, Peter .

VACCINE, 2006, 24 (26) :5452-5460

[2] The success and failure of BCG - implications for a novel tuberculosis vaccine [J].

Andersen, P ;

Doherty, TM .

NATURE REVIEWS MICROBIOLOGY, 2005, 3 (08) :656-662

[3] Vaccine strategies against latent tuberculosis infection [J].

Andersen, Peter .

TRENDS IN MICROBIOLOGY, 2007, 15 (01) :7-13

[4]

BIO Ventures for Global Health, 2006, TUB VACC CAS INV

[5] Exchanging ESAT6 with TB10.4 in an Ag85B fusion molecule-based tuberculosis subunit vaccine: Efficient protection and ESAT6-based sensitive monitoring of vaccine efficacy [J].

Dietrich, J ;

Aagaard, C ;

Leah, R ;

Olsen, AW ;

Stryhn, A ;

Doherty, TM ;

Andersen, P .

JOURNAL OF IMMUNOLOGY, 2005, 174 (10) :6332-6339

[6] Mucosal administration of Ag85B-ESAT-6 protects against infection with Mycobacterium tuberculosis and boosts prior bacillus Calmette-Guerin immunity [J].

Dietrich, Jes ;

Andersen, Claire ;

Rappuoli, Rino ;

Doherty, T. Mark ;

Jensen, Charlotte Green ;

Andersen, Peter .

JOURNAL OF IMMUNOLOGY, 2006, 177 (09) :6353-6360

[7] Global epidemiology of tuberculosis [J].

Dye, C .

LANCET, 2006, 367 (9514) :938-940

[8] Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guerin mutants that secrete listeriolysin [J].

Grode, L ;

Seiler, P ;

Baumann, S ;

Hess, J ;

Brinkmann, V ;

Eddine, AN ;

Mann, P ;

Goosmann, C ;

Bandermann, S ;

Smith, D ;

Bancroft, GJ ;

Reyrat, JM ;

van Soolingen, D ;

Raupach, B ;

Kaufmann, SHE .

JOURNAL OF CLINICAL INVESTIGATION, 2005, 115 (09) :2472-2479

[9] A new vaccine against tuberculosis affords greater survival after challenge than the current vaccine in the guinea pig model of pulmonary tuberculosis [J].

Horwitz, MA ;

Harth, G .

INFECTION AND IMMUNITY, 2003, 71 (04) :1672-1679

[10] New live mycobacterial vaccines: the Geneva consensus on essential steps towards clinical development [J].

Kamath, AT ;

Fruth, UL ;

Brennan, MJ ;

Dobbelaer, R ;

Hubrechts, P ;

Ho, MM ;

Mayner, RE ;

Thole, J ;

Walker, KB ;

Liu, M ;

Lambert, PH .

VACCINE, 2005, 23 (29) :3753-3761

← 1 2 →