The association between apo E genotype and depressive symptoms in elderly African-American subjects

被引：17

作者：

Class, CA

Unverzagt, FW

Gao, SJ

Sahota, A

Hall, KS

Hendrie, HC

机构：

[1] INDIANA UNIV,SCH MED,DEPT MED,INDIANAPOLIS,IN 46202

[2] INDIANA UNIV,SCH MED,DEPT MED & MOL GENET,INDIANAPOLIS,IN 46202

来源：

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY | 1997年 / 5卷 / 04期

关键词：

D O I：

10.1097/00019442-199700540-00009

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

In this study of 138 elderly subjects (112 without and 26 with dementia) obtained from a community sample of elderly African-American subjects, there were no significant differences in mean Geriatric Depression Scale scores by APo E epsilon 4 status for dementia or nondementia subjects. Three subjects received a diagnosis of major depressive disorder. None of these subjects were APo E epsilon 4-positive. These results do not support an association between depressive symptoms and Apo E allele status in this elderly African-American population.

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页码：339 / 343

页数：5

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