Vitamin D Deficiency and Tuberculosis Progression

被引:161
作者
Talat, Najeeha
Perry, Sharon [2 ]
Parsonnet, Julie [2 ]
Dawood, Ghaffar [3 ]
Hussain, Rabia [1 ]
机构
[1] Aga Khan Univ, Dept Pathol & Microbiol, Karachi 74800, Pakistan
[2] Stanford Univ, Sch Med, Stanford, CA 94305 USA
[3] Masoomeen Gen Hosp, Karachi, Pakistan
关键词
D O I
10.3201/eid1605.091693
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
To assess the association between vitamin D deficiency and tuberculosis disease progression, we studied vitamin D levels in a cohort of tuberculosis patients and their contacts (N = 129) in Pakistan. Most (79%) persons showed deficiency. Low vitamin D levels were associated with a 5-fold increased risk for progression to tuberculosis.
引用
收藏
页码:853 / 855
页数:3
相关论文
共 15 条
[11]   Low serum vitamin D levels and tuberculosis: a systematic review and meta-analysis [J].
Nnoaham, Kelechi E. ;
Clarke, Aileen .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2008, 37 (01) :113-119
[12]   L-arginine and vitamin D: novel adjunctive immunotherapies in tuberculosis [J].
Ralph, Anna P. ;
Kelly, Paul M. ;
Anstey, Nicholas M. .
TRENDS IN MICROBIOLOGY, 2008, 16 (07) :336-344
[13]   THE ROLE OF VITAMIN-D IN TUBERCULOSIS [J].
ROOK, GAW .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1988, 138 (04) :768-770
[14]   Vitamin D as Supplementary Treatment for Tuberculosis A Double-blind, Randomized, Placebo-controlled Trial [J].
Wejse, Christian ;
Gomes, Victor F. ;
Rabna, Paulo ;
Gustafson, Per ;
Aaby, Peter ;
Lisse, Ida M. ;
Andersen, Paul L. ;
Glerup, Henning ;
Sodemann, Morten .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2009, 179 (09) :843-850
[15]  
Zuberi Lubna M, 2008, J Pak Med Assoc, V58, P482