Modulation of contextual fear conditioning by chronic stress in rats is related to individual differences in behavioral reactivity to novelty

被引：29

作者：

Cordero, MI ^{[1
]}

Kruyt, ND ^{[1
]}

Sandi, C ^{[1
]}

机构：

[1] Univ Nacl Educ Distancia, Dept Psychobiol, E-28040 Madrid, Spain

来源：

BRAIN RESEARCH | 2003年 / 970卷 / 1-2期

关键词：

individual difference; fear conditioning; chronic stress; locomotor reactivity; learning; memory;

D O I：

10.1016/S0006-8993(03)02352-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We investigated whether contextual fear conditioning could be related to the behavioral trait of locomotor reactivity to novelty in undisturbed and chronically stressed rats. Fear conditioning was found to be specifically enhanced in low reactive-stressed animals, as compared to low reactive-undisturbed rats. The results suggest that individuals that display low reactivity to novelty are more susceptible to be influenced by stress exposure to subsequently exhibit potentiated contextual fear conditioning. (C) 2003 Elsevier Science B.V. All rights reserved.

引用

页码：242 / 245

页数：4

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