Protein kinase C isoenzymes: a review of their structure, regulation and role in regulating airways smooth muscle tone and mitogenesis

被引：142

作者：

Webb, BLJ

Hirst, SJ

Giembycz, MA

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Sch Med, Natl Heart & Lung Inst, London SW3 6LY, England

[2] Imperial Canc Res Fund, Prot Phosphorylat Lab, London WC2A 3PX, England

[3] Kings Coll London, Dept Resp Med & Allergy, GKT, Sch Med, London SE1 9RT, England

来源：

BRITISH JOURNAL OF PHARMACOLOGY | 2000年 / 130卷 / 07期

关键词：

protein kinase C; mitogenesis; airways smooth muscle; contraction;

D O I：

10.1038/sj.bjp.0703452

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

[No abstract available]

引用

页码：1433 / 1452

页数：20

共 261 条

[21] Actions of neurotransmitters and other messengers on Ca2+ channels and K+ channels in smooth muscle cells [J].

Beech, DJ .

PHARMACOLOGY & THERAPEUTICS, 1997, 73 (02) :91-119

[22]

BELL RM, 1991, J BIOL CHEM, V266, P4661

[23]

BENGUR AR, 1987, J BIOL CHEM, V262, P7613

[24] ANGIOTENSIN-II-STIMULATED PROTEIN-SYNTHESIS IN CULTURED VASCULAR SMOOTH-MUSCLE CELLS [J].

BERK, BC ;

VEKSHTEIN, V ;

GORDON, HM ;

TSUDA, T .

HYPERTENSION, 1989, 13 (04) :305-314

[25]

BERK BC, 1987, J BIOL CHEM, V262, P5057

[26] PROTEIN KINASE-C-ZETA ISOFORM IS CRITICAL FOR MITOGENIC SIGNAL-TRANSDUCTION [J].

BERRA, E ;

DIAZMECO, MT ;

DOMINGUEZ, I ;

MUNICIO, MM ;

SANZ, L ;

LOZANO, J ;

CHAPKIN, RS ;

MOSCAT, J .

CELL, 1993, 74 (03) :555-563

[27]

BLACK J, 1998, AM J RESP CRIT CARE, V157, pA428

[28] Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase C alpha [J].

Bornancin, F ;

Parker, PJ .

CURRENT BIOLOGY, 1996, 6 (09) :1114-1123

[29] Phosphorylation of protein kinase C-zeta on serine 657 controls the accumulation of active enzyme and contributes to its phosphatase-resistant state [J].

Bornancin, F ;

Parker, PJ .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (06) :3544-3549

[30] Role of protein kinase C in calcium sensitization during muscarinic stimulation in airway smooth muscle [J].

Bremerich, DH ;

Warner, DO ;

Lorenz, RR ;

Shumway, R ;

Jones, KA .

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 1997, 273 (04) :L775-L781

← 1 2 3 4 5 6 7 8 9 10 →