Antibody mediated protection against intracellular pathogens

被引：95

作者：

Casadevall, A

机构：

[1] Yeshiva Univ Albert Einstein Coll Med, Dept Med, Div Infect Dis, Bronx, NY 10461 USA

[2] Yeshiva Univ Albert Einstein Coll Med, Dept Microbiol & Immunol, Bronx, NY 10461 USA

来源：

TRENDS IN MICROBIOLOGY | 1998年 / 6卷 / 03期

关键词：

D O I：

10.1016/S0966-842X(98)01208-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The view that antibody-mediated protection is unimportant against intracellular pathogens is not supported by the literature. In fact, there is convincing evidence that antibody call protect against many important intracellular pathogens. The challenge now is to identify antigens that elicit protective antibodies, use them in vaccine design and understand how humoral and cellular immune mechanisms cooperate.

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页码：102 / 107

页数：6

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