Signaling angiogenesis and lymphangiogenesis

被引:160
作者
Korpelainen, EI [1 ]
Alitalo, K [1 ]
机构
[1] Univ Helsinki, Haartman Inst, Mol Canc Biol Lab, FIN-00014 Helsinki, Finland
关键词
D O I
10.1016/S0955-0674(98)80137-3
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Exciting progress has been made in elucidating the complex network of receptor-ligand interactions that regulate blood vessel growth. Understanding these control mechanisms is of interest not only because of their role in developmental biology, but because they provide potential therapeutic strategies for disease processes involving angiogenesis, such as tumor growth. (C) Current Biology Ltd ISSN 0955-0674.
引用
收藏
页码:159 / 164
页数:6
相关论文
共 59 条
  • [41] Genomic organization of the mouse and human genes for vascular endothelial growth factor B (VEGF-B) and characterization of a second splice isoform
    Olofsson, B
    Pajusola, K
    vonEuler, G
    Chilov, D
    Alitalo, K
    Eriksson, U
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (32) : 19310 - 19317
  • [42] Vascular endothelial growth factor B, a novel growth factor for endothelial cells
    Olofsson, B
    Pajusola, K
    Kaipainen, A
    vonEuler, G
    Joukov, V
    Saksela, O
    Orpana, A
    Petersson, RF
    Alitalo, K
    Eriksson, U
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (06) : 2576 - 2581
  • [43] Angiostatin induces and sustains dormancy of human primary tumors in mice
    OReilly, MS
    Holmgren, L
    Chen, C
    Folkman, J
    [J]. NATURE MEDICINE, 1996, 2 (06) : 689 - 692
  • [44] ANGIOSTATIN - A NOVEL ANGIOGENESIS INHIBITOR THAT MEDIATES THE SUPPRESSION OF METASTASES BY A LEWIS LUNG-CARCINOMA
    OREILLY, MS
    HOLMGREN, L
    SHING, Y
    CHEN, C
    ROSENTHAL, RA
    MOSES, M
    LANE, WS
    CAO, YH
    SAGE, EH
    FOLKMAN, J
    [J]. CELL, 1994, 79 (02) : 315 - 328
  • [45] Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
    OReilly, MS
    Boehm, T
    Shing, Y
    Fukai, N
    Vasios, G
    Lane, WS
    Flynn, E
    Birkhead, JR
    Olsen, BR
    Folkman, J
    [J]. CELL, 1997, 88 (02) : 277 - 285
  • [46] Identification of a c-fos-induced gene that is related to the platelet-derived growth factor vascular endothelial growth factor family
    Orlandini, M
    Marconcini, L
    Ferruzzi, R
    Oliviero, S
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (21) : 11675 - 11680
  • [47] TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis
    Oshima, M
    Oshima, H
    Taketo, MM
    [J]. DEVELOPMENTAL BIOLOGY, 1996, 179 (01) : 297 - 302
  • [48] PARK JE, 1994, J BIOL CHEM, V269, P25646
  • [49] Partanen J, 1996, DEVELOPMENT, V122, P3013
  • [50] THE RECEPTOR TYROSINE KINASE TIE IS REQUIRED FOR INTEGRITY AND SURVIVAL OF VASCULAR ENDOTHELIAL-CELLS
    PURI, MC
    ROSSANT, J
    ALITALO, K
    BERNSTEIN, A
    PARTANEN, J
    [J]. EMBO JOURNAL, 1995, 14 (23) : 5884 - 5891