Understanding the electroporation of cells and artificial bilayer membranes

被引：85

作者：

Isambert, H ^{[1
]}

机构：

[1] Cornell Univ, Dept Phys, Ithaca, NY 14853 USA

来源：

PHYSICAL REVIEW LETTERS | 1998年 / 80卷 / 15期

关键词：

D O I：

10.1103/PhysRevLett.80.3404

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

A new physical mechanism is proposed to explain the electroporation of cells based on the electric-field-induced stretching of their curved membrane. The opening of pores simultaneously relaxes the surface tension leaving long-lived pores in the membrane. Semiquantitative results are proposed in good agreement with experimental observations on cells and artificial bilayer membranes.

引用

页码：3404 / 3407

页数：4

共 13 条

[11] KINETICS OF PORE-SIZE DURING IRREVERSIBLE ELECTRICAL BREAKDOWN OF LIPID BILAYER-MEMBRANES [J].