Synthesis and biological activity of novel antibacterial quinazolines

被引:118
作者
Bedi, PMS [1 ]
Kumar, V
Mahajan, MP
机构
[1] Guru Nanak Dev Univ, Dept Pharmaceut Sci, Amritsar 143005, Punjab, India
[2] Guru Nanak Dev Univ, Dept Appl Chem, Amritsar 143005, Punjab, India
关键词
quinazoline; antibacterial; resistant bacteria;
D O I
10.1016/j.bmcl.2004.07.065
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Novel quinazolines, having interesting antibacterial activity have been prepared, characterized and tested against a panel of susceptible and resistant Gram positive and Gram negative organisms. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:5211 / 5213
页数:3
相关论文
共 21 条
[1]   Amidine derived 1,3-diazabuta-1,3-dienes as potential antibacterial and antifungal agents [J].
Bedi, PMS ;
Mahajan, MP ;
Kapoor, VK .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 14 (14) :3821-3824
[2]  
Bedi PMS, 2003, PDA J PHARM SCI TECH, V57, P109
[3]  
BEDI PMS, 2004, INDIAN J PHARM SCI, V66, P112
[4]  
Fromtling Robert A., 1996, Drugs of the Future, V21, P496
[5]  
GIRI S, 1982, INDIAN J CHEM B, V21, P377
[6]   SYNTHESIS OF SOME BIS-(OXADIAZOLYL)SULPHIDES, SULFONES AND 2-SUBSTITUTED-[1,3,4]-OXADIAZOLO-[2,3,B] QUINAZOL-5-ONES AS POTENTIAL FUNGICIDES [J].
GIRI, S ;
NIZAMUDDIN .
AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1978, 42 (01) :41-44
[7]  
GUJRAL M. L., 1955, INDIAN JOUR MED RES, V43, P637
[8]  
GUPTA DP, 1988, INDIAN J CHEM B, V27, P1060
[9]  
JAIN PK, 1980, INDIAN J MED RES, V71, P402
[10]   Tandem [4+2] cycloaddition versus electrocyclisation reactions of 1-aryl-2-phenyl-5-alkyl/aryl-1,3-diazapenta-1,3,4-trienes in aza-Wittig reactions of N′-aryl-N-(triphenylphosphoranlidene)benzenecarboximidamides with ketenes [J].
Jayakumar, S ;
Kumar, V ;
Mahajan, MP .
TETRAHEDRON LETTERS, 2001, 42 (11) :2235-2237