Protein-silicone interactions: How compatible are the two species?

被引：15

作者：

Bartzoka, V

Brook, MA

McDermott, MR

机构：

[1] McMaster Univ, Dept Chem, Hamilton, ON L8S 4M1, Canada

[2] McMaster Univ, Dept Pathol, Hamilton, ON L8N 3Z5, Canada

来源：

LANGMUIR | 1998年 / 14卷 / 07期

关键词：

D O I：

10.1021/la9711140

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Protein-on-silicone and silicone-on-protein films mere made by the sequential coating of the human serum albumin (HSA) onto silicone films on glass or vice versa. The silicones used were either trimethylsilyl-terminated poly(dimethylsiloxane) (unfunctionalized PDMS) or (triethoxysilyl)propyl-terminated poly(dimethylsiloxane) (functionalized TES-PDMS). Angular-dependent X-ray photoelectron spectroscopy (AD-XPS) and contact angle measurements (CA) were used to characterize the modified surfaces. Irrespective of the order of building the films, protein-on-silicone or silicone-on-protein both showed essentially identical surface compositions, suggesting a significant degree of mixing between the protein and silicone. The TES-PDMS was found to have a greater affinity for HSA: thicker and more homogeneous silicone films were found with TES-PDMS/HSA than with PDMS/HSA films.

引用

页码：1887 / 1891

页数：5

共 25 条

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