Freeze-drying of poly((2-dimethylamino)ethyl methacrylate)-based gene delivery systems

被引:53
作者
Cherng, JY [1 ]
van de Wetering, P [1 ]
Talsma, H [1 ]
Crommelin, DJA [1 ]
Hennink, WE [1 ]
机构
[1] Univ Utrecht, Dept Pharmaceut, Utrecht Inst Pharmaceut Sci, GUIDE,Res Sch, NL-3508 TB Utrecht, Netherlands
关键词
plasmid; poly(2-dimethylamino)ethyl methacrylate; freeze-drying; gene therapy;
D O I
10.1023/A:1012164804441
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
[No abstract available]
引用
收藏
页码:1838 / 1841
页数:4
相关论文
共 11 条
  • [1] FACTORS AFFECTING SHORT-TERM AND LONG-TERM STABILITIES OF PROTEINS
    ARAKAWA, T
    PRESTRELSKI, SJ
    KENNEY, WC
    CARPENTER, JF
    [J]. ADVANCED DRUG DELIVERY REVIEWS, 1993, 10 (01) : 1 - 28
  • [2] INVIVO TRANSFER AND EXPRESSION OF THE LACZ GENE IN THE MOUSE LUNG
    BOUT, A
    VALERIO, D
    SCHOLTE, BJ
    [J]. EXPERIMENTAL LUNG RESEARCH, 1993, 19 (02) : 193 - 202
  • [3] USE OF SUBAMBIENT THERMAL-ANALYSIS TO OPTIMIZE PROTEIN LYOPHILIZATION
    CHANG, BS
    RANDALL, CS
    [J]. CRYOBIOLOGY, 1992, 29 (05) : 632 - 656
  • [4] Effect of size and serum proteins on transfection efficiency of poly((2-dimethylamino)ethyl methacrylate)-plasmid nanoparticles
    Cherng, JY
    vandeWetering, P
    Talsma, H
    Crommelin, DJA
    Hennink, WE
    [J]. PHARMACEUTICAL RESEARCH, 1996, 13 (07) : 1038 - 1042
  • [5] Ciftci K., 1996, Pharmaceutical Research (New York), V13, pS390
  • [6] LYOPHILIZED FORMULATIONS OF RECOMBINANT TUMOR-NECROSIS-FACTOR
    HORA, MS
    RANA, RK
    SMITH, FW
    [J]. PHARMACEUTICAL RESEARCH, 1992, 9 (01) : 33 - 36
  • [7] READING M, 1993, TRENDS POLYM SCI, V1, P248
  • [8] RESSING ME, 1992, PHARMACEUT RES, V9, P226
  • [9] Relation between transfection efficiency and cytotoxicity of poly(2-(dimethylamino)ethyl methacrylate)/plasmid complexes
    vandeWetering, P
    Cherng, JY
    Talsma, H
    Hennink, WE
    [J]. JOURNAL OF CONTROLLED RELEASE, 1997, 49 (01) : 59 - 69
  • [10] VANWINDEN ECA, IN PRESS EUR J PHARM