Review of neuroimaging studies of child and adolescent psychiatric disorders from the past 10 years

被引:81
作者
Hendren, RL
De Backer, I
Pandina, GJ
机构
[1] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Inst Qual Res & Training, New Brunswick, NJ 08901 USA
[2] Univ Med & Dent New Jersey, New Jersey Med Sch, Inst Qual Res & Training, New Brunswick, NJ USA
[3] Univ Med & Dent New Jersey, Univ Behav Hlth Care, Inst Qual Res & Training, Newark, NJ 07103 USA
[4] Univ Louvain, Louvain, Belgium
关键词
neuroimaging; serious emotional disorders; neurodevelopmental psychiatric disorders;
D O I
10.1097/00004583-200007000-00010
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
Objectives: To review recent neuroimaging studies of serious emotional disorders in youth and identify problems and promise of neuroimaging in clinical practice. Method: Published reports from refereed journals are briefly described, critiqued, and synthesized into a summary of the findings to date. Results: Childhood-onset schizophrenia shows progressive ventricular enlargement, reduction in total brain and thalamus volume, changes in temporal lobe structures, and reductions in frontal metabolism. Autistic disorder is associated with cerebellar changes, greater total brain and lateral ventricle volume, and asymmetry. The prefrontal cortex and the basal ganglia are consistently reported as abnormal in attention-deficit/hyperactivity disorder. Patients with anorexia nervosa show enlarged CSF spaces and reductions in gray and white matter that are only partially reversible with weight recovery. Conclusions: Results from neuroimaging studies of childhood-onset psychiatric disorders suggest consistency in the structures found to be abnormal, but inconsistencies in the nature of these abnormalities. Although neuroimaging technology holds great promise for neurodevelopmental research, it is not yet a diagnostic instrument.
引用
收藏
页码:815 / 828
页数:14
相关论文
共 90 条
[1]  
AlaghbandRad J, 1997, AM J PSYCHIAT, V154, P64
[2]  
Amen D G, 1997, Ann Clin Psychiatry, V9, P81, DOI 10.3109/10401239709147778
[3]  
[Anonymous], EUROPEAN CHILD ADOLE
[4]   ASYMMETRY OF THE VENTRICLE AND AGE AT THE ONSET OF SCHIZOPHRENIA [J].
ASO, M ;
KURACHI, M ;
SUZUKI, M ;
YUASA, S ;
MATSUI, M ;
SAITOH, O .
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, 1995, 245 (03) :142-144
[5]  
Aylward EH, 1996, ARCH GEN PSYCHIAT, V53, P577
[6]   Corpus callosum morphology in children with Tourette syndrome and attention deficit hyperactivity disorder [J].
Baumgardner, TL ;
Singer, HS ;
Denckla, MB ;
Rubin, MA ;
Abrams, MT ;
Colli, MJ ;
Reiss, AL .
NEUROLOGY, 1996, 47 (02) :477-482
[7]   Cerebellum in attention-deficit hyperactivity disorder - A morphometric MRI study [J].
Berquin, PC ;
Giedd, JN ;
Jacobsen, LK ;
Hamburger, SD ;
Krain, AL ;
Rapoport, JL ;
Castellanos, FX .
NEUROLOGY, 1998, 50 (04) :1087-1093
[8]  
BERROLINO A, 1998, AM J PSYCHIAT, V155, P1376
[9]  
Berthier M L, 1990, J Neuropsychiatry Clin Neurosci, V2, P197
[10]   MAGNETIC-RESONANCE-IMAGING IN PATIENTS WITH CONCURRENT TOURETTE DISORDER AND ASPERGER SYNDROME [J].
BERTHIER, ML ;
BAYES, A ;
TOLOSA, ES .
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 1993, 32 (03) :633-639