Keeping p53 in Check: A High-Stakes Balancing Act

被引：22

作者：

Berger, Shelley L. ^{[1
,2
,3
]}

机构：

[1] Univ Penn, Dept Cell & Dev Biol, Philadelphia, PA 19104 USA

[2] Univ Penn, Dept Genet, Philadelphia, PA 19104 USA

[3] Univ Penn, Dept Biol, Philadelphia, PA 19104 USA

来源：

CELL | 2010年 / 142卷 / 01期

关键词：

D O I：

10.1016/j.cell.2010.06.026

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：17 / 19

页数：3

共 7 条

[1] The emerging field of dynamic lysine methylation of non-histone proteins [J].

Huang, Jing ;

Berger, Shelley L. .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 2008, 18 (02) :152-158

[2] p53 is regulated by the lysine demethylase LSD1 [J].

Huang, Jing ;

Sengupta, Roopsha ;

Espejo, Alexsandra B. ;

Lee, Min Gyu ;

Dorsey, Jean A. ;

Richter, Mario ;

Opravil, Susanne ;

Shiekhattar, Ramin ;

Bedford, Mark T. ;

Jenuwein, Thomas ;

Berger, Shelley L. .

NATURE, 2007, 449 (7158) :105-U80

[3] G9a and Glp Methylate Lysine 373 in the Tumor Suppressor p53 [J].

Huang, Jing ;

Dorsey, Jean ;

Chuikov, Sergei ;

Zhang, Xinyue ;

Jenuwein, Thomas ;

Reinberg, Danny ;

Berger, Shelley L. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (13) :9636-9641

[4] Modes of p53 Regulation [J].

Kruse, Jan-Philipp ;

Gu, Wei .

CELL, 2009, 137 (04) :609-622

[5] Acetylation is indispensable for p53 activation [J].

Tang, Yi ;

Zhao, Wenhui ;

Chen, Yue ;

Zhao, Yingming ;

Gu, Wei .

CELL, 2008, 133 (04) :612-626

[6] Regulating the p53 pathway:: in vitro hypotheses, in vivo veritas [J].

Toledo, Franck ;

Wahl, Geoffrey M. .

NATURE REVIEWS CANCER, 2006, 6 (12) :909-923

[7] Blinded by the Light: The Growing Complexity of p53 [J].

Vousden, Karen H. ;

Prives, Carol .

CELL, 2009, 137 (03) :413-431

← 1 →