More peptides and other diverse constituents of the marine mollusk Philinopsis speciosa

被引：56

作者：

Nakao, Y ^{[1
]}

Yoshida, WY ^{[1
]}

Szabo, CM ^{[1
]}

Baker, BJ ^{[1
]}

Scheuer, PJ ^{[1
]}

机构：

[1] Univ Hawaii Manoa, Dept Chem, Honolulu, HI 96822 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1998年 / 63卷 / 10期

关键词：

D O I：

10.1021/jo9719867

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In addition to five new depsipeptides related to kulolide-1 (1), further examination of the mollusk Philinopsis speciosa has yielded a linear peptide, pupukeamide (14), and an unprecedented macrolide, tolytoxin-23-acetate (7). Chemical makeup suggested that the compounds originate from blue-green algae and are transmitted via herbivorous mollusks to P, speciosa. This could be verified by laboratory experiment. The structures were determined largely by spectroscopic techniques and the stereochemistry by hydrolysis of the peptides followed by chiral chromatography.

引用

页码：3272 / 3280

页数：9