Procyanidin B1 is detected in human serum after intake of proanthocyanidin-rich grape seed extract

被引：183

作者：

Sano, A

Yamakoshi, J

Tokutake, S

Tobe, K

Kubota, Y

Kikuchi, M

机构：

[1] Kikkoman Foods Inc, Div Res & Dev, Chiba 2780037, Japan

[2] Kikkoman Gen Hosp, Chiba 2780005, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2003年 / 67卷 / 05期

关键词：

proanthocyanidin; procyanidin B1; absorption; grape seed extract; human;

D O I：

10.1271/bbb.67.1140

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

To confirm the absorption of proanthocyanidin (PA) into the human body, four healthy adults were administered 2.0 g of PA-rich grape seed extract (GSE). Blood were drawn before intake and 2 h after intake. Through the enzymatic treatment of sulfatase and beta-glucuronidase, blood samples were analyzed by HPLC coupled with mass-spectrometry (LC/MS). Procyanidin B1 [epicatechin-(4beta-->8)-catechin] was detected in human serum 2 h after intake. Its concentration was 10.6+/-2.5 nmol/l.

引用

页码：1140 / 1143

页数：4

共 20 条

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