An inhibitor of aldose reductase and sorbitol accumulation from Anthocepharus chinensis

被引：19

作者：

Haraguchi, H

Kanada, M

Fukuda, A

Naruse, K

Okamura, N

Yagi, A

机构：

[1] Fukuyama Univ, Fac Engn, Fukuyama, Hiroshima 72902, Japan

[2] Fukuyama Univ, Fac Pharm & Pharmaceut Sci, Fukuyama, Hiroshima 72902, Japan

来源：

PLANTA MEDICA | 1998年 / 64卷 / 01期

关键词：

D O I：

10.1055/s-2006-957369

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A flavonoid glycoside was isolated from Anthocepharus chinensis. Its structure was elucidated by spectral data and determined to be myricetin 3-O-(4 "-acetyl)-alpha-fucoside. This flavonoid glycoside and its aglycone showed potent inhibition against rat and lens aldose reductase. The flavonoid aglycone also inhibited sorbitol accumulation in human red blood cells.

引用

收藏

页码：68 / 69

页数：2

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