A supramolecular approach to organic alloys:: Cocrystals and three- and four-component solid solutions of 1,4-diazabicyclo[2.2.2]octane and 4-X-phenols (X = Cl, CH3, Br)

被引：76

作者：

Dabros, Marta ^{[1
]}

Emery, Paul R. ^{[1
]}

Thalladi, Venkat R. ^{[1
]}

机构：

[1] Worcester Polytech Inst, Dept Chem & Biochem, Worcester, MA 01609 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 22期

关键词：

crystal engineering; organic alloys; phenols; solid solutions; supramolecular chemistry;

D O I：

10.1002/anie.200604830

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Triple play: The crystallization of 1,4-diazabicyclo[2. 2.2]octane (A) with one, two, or three different 4-substituted phenols (B, C, D) leads to cocrystals (for example, AB2, left) or solid solutions (for example, A(B,C,D)2, right). The repeat units of these multicomponent organic solids are supramolecular assemblies of three molecules. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：4132 / 4135

页数：4

共 23 条

[1]

Aakeroy C. B., 2001, ANGEW CHEM, V113, P3340

[2] Supramolecular reagents:: versatile tools for non-covalent synthesis [J].

Aakeröy, CB ;

Desper, J ;

Urbina, JF .

CHEMICAL COMMUNICATIONS, 2005, (22) :2820-2822

[3]

Aakeröy CB, 2001, ANGEW CHEM INT EDIT, V40, P3240, DOI 10.1002/1521-3773(20010903)40:17<3240::AID-ANIE3240>3.0.CO

[4]

2-X

[5] Crystal engineering of the composition of pharmaceutical phases.: Do pharmaceutical co-crystals represent a new path to improved medicines? [J].

Almarsson, Ö ;

Zaworotko, MJ .

CHEMICAL COMMUNICATIONS, 2004, (17) :1889-1896

[6] Three-component carboxylic acid-bipyridine lattice inclusion host. Supramolecular synthesis of ternary cocrystals [J].

Bhogala, BR ;

Basavoju, S ;

Nangia, A .

CRYSTAL GROWTH & DESIGN, 2005, 5 (05) :1683-1686

[7] Hybrid insulin cocrystals for controlled release delivery [J].

Brader, ML ;

Sukumar, M ;

Pekar, AH ;

McClellan, DS ;

Chance, RE ;

Flora, DB ;

Cox, AL ;

Irwin, L ;

Myers, SR .

NATURE BIOTECHNOLOGY, 2002, 20 (08) :800-804

[8] Direct structure determination of a multicomponent molecular crystal prepared by a solid-state grinding procedure [J].

Cheung, EY ;

Kitchin, SJ ;

Harris, KDM ;

Imai, Y ;

Tajima, N ;

Kuroda, R .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (48) :14658-+

[9]

Desiraju G. R., 1989, DESIGN ORGANIC SOLID

[10] HYDROGEN-BONDS AS DESIGN ELEMENTS IN ORGANIC-CHEMISTRY [J].

ETTER, MC .

JOURNAL OF PHYSICAL CHEMISTRY, 1991, 95 (12) :4601-4610

← 1 2 3 →