Learning in ex-vivo developing networks of cortical neurons

被引:29
作者
Marom, S [1 ]
Eytan, D [1 ]
机构
[1] Technion Israel Inst Technol, Fac Med, Dept Physiol & Biophys, IL-32000 Haifa, Israel
来源
DEVELOPMENT, DYNAMICS AND PATHOLOGY OF NEURONAL NETWORKS: FROM MOLECULES TO FUNCTIONAL CIRCUITS | 2005年 / 147卷
关键词
RAT NEOCORTICAL NEURONS; CEREBRAL-CORTEX; ELECTRICAL-ACTIVITY; DEVELOPMENT INVITRO; FIRING PATTERNS; CELL-CULTURE; IN-VITRO; REWARD; DOPAMINE; PICROTOXIN;
D O I
10.1016/S0079-6123(04)47014-9
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
This contribution describes the use of multi-site interaction with large cortical networks in the study of learning. The general physiological properties of the network are described, and the concept of learning is mapped to the experimental network preparation. Learning is then analyzed in terms of exploration (defined as changes in the configuration of associations within the biological network) and recognition (the stabilization of "worthy" associations).
引用
收藏
页码:189 / 199
页数:11
相关论文
共 53 条
[11]  
Freud S., 1895, STANDARD EDITION, V1, P283
[12]   Computational models of association cortex [J].
Gisiger, T ;
Dehaene, S ;
Changeux, JP .
CURRENT OPINION IN NEUROBIOLOGY, 2000, 10 (02) :250-259
[13]   Auditory cortical neurons in vitro: Cell culture and multichannel extracellular recording [J].
Gopal, KV ;
Gross, GW .
ACTA OTO-LARYNGOLOGICA, 1996, 116 (05) :690-696
[14]   SIMULTANEOUS SINGLE UNIT RECORDING INVITRO WITH A PHOTOETCHED LASER DEINSULATED GOLD MULTI-MICRO-ELECTRODE SURFACE [J].
GROSS, GW .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1979, 26 (05) :273-279
[15]   RECORDING OF SPONTANEOUS ACTIVITY WITH PHOTOETCHED MICROELECTRODE SURFACES FROM MOUSE SPINAL NEURONS IN CULTURE [J].
GROSS, GW ;
WILLIAMS, AN ;
LUCAS, JH .
JOURNAL OF NEUROSCIENCE METHODS, 1982, 5 (1-2) :13-22
[16]  
GUTHRIE ER, 1946, PSYCHOL B, V43
[17]   SPONTANEOUS NEURONAL FIRING PATTERNS IN FETAL-RAT CORTICAL NETWORKS DURING DEVELOPMENT INVITRO - A QUANTITATIVE-ANALYSIS [J].
HABETS, AMMC ;
VANDONGEN, AMJ ;
VANHUIZEN, F ;
CORNER, MA .
EXPERIMENTAL BRAIN RESEARCH, 1987, 69 (01) :43-52
[18]  
Hebb D.O., 1949, The organization of behavior
[19]  
a neuropsychological theory
[20]  
Higgins D., 1998, CULTURING NERVE CELL, P37