A Graphene Oxide Based Immuno-biosensor for Pathogen Detection

被引：480

作者：

Jung, Jae Hwan ^{[1
]}

Cheon, Doo Sung ^{[2
]}

Liu, Fei ^{[1
]}

Lee, Kang Bum ^{[2
]}

Seo, Tae Seok ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol, Dept Chem & Biomol Engn, 373-1 Guseong Dong, Taejon 305701, South Korea

[2] Korea Ctr Dis Control & Prevent KCDC, Div Enter & Hepatitis Viruses, Seoul 122701, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 33期

关键词：

biosensors; fluorescence; FRET; graphene nanoparticles; RESONANCE ENERGY-TRANSFER; GOLD NANOPARTICLES; DNA; HYBRIDIZATION; INTERLINKER; REDUCTION; DELIVERY; PLATFORM;

D O I：

10.1002/anie.201001428

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Don't FRET when I GO: Sensitive and selective rotavirus detection is achieved by using the photoluminescence of a graphene oxide (CO) array. The target cell was captured by the rotavirus-specific antibody immobilized on the CO array, and the binding event was monitored by observing the fluorescence quenching that results from fluorescence resonance energy transfer (FRET) between CO and gold nanoparticles linked to the antibodies (see picture). © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：5708 / 5711

页数：4

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