A new chiral catalyst for the enantioselective Strecker synthesis of α-amino acids

被引：102

作者：

Huang, JK ^{[1
]}

Corey, EJ ^{[1
]}

机构：

[1] Harvard Univ, Dept Chem & Biol Chem, Cambridge, MA 02138 USA

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 26期

关键词：

D O I：

10.1021/ol047698w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The chiral ammonium salt 3 is demonstrated to be an effective catalyst for the highly enantioselective Strecker reaction of N-allylbenzaldimines with hydrogen cyanide in CH2Cl2 solution.

引用

页码：5027 / 5029

页数：3

共 41 条

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[7] THE APPLICATION OF A MECHANISTIC MODEL LEADS TO THE EXTENSION OF THE SHARPLESS ASYMMETRIC DIHYDROXYLATION TO ALLYLIC 4-METHOXYBENZOATES AND CONFORMATIONALLY RELATED AMINE AND HOMOALLYLIC ALCOHOL DERIVATIVES
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