Opinion -: Therapeutic vaccines against HIV need international partnerships

被引:29
作者
Autran, B [1 ]
Debré, P
Walker, B
Katlama, C
机构
[1] CHU Pitie Salpetriere, Lab Immunol Cellulaire, Serv Malad Infect, F-75651 Paris, France
[2] Massachusetts Gen Hosp, Partners AIDS Res Ctr, Howard Hughes Med Inst, Boston, MA 02129 USA
[3] Harvard Univ, Sch Med, Div AIDS, Boston, MA 02129 USA
关键词
D O I
10.1038/nri1107
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The successes of anti-retroviral treatments against HIV are limited today by the cost and toxicity of lifelong administration. An innovative therapeutic strategy has been proposed to boost the immune system of infected patients with HIV vaccines and to help limit the use of anti-retroviral treatments. This perspective article reviews the crucial questions raised by such a strategy and the main international efforts that are already set up to provide rapid answers - in particular, a not-for-profit international network that is dedicated to the development of therapeutic immunization programmes against HIV.
引用
收藏
页码:503 / 508
页数:6
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