iPfam:: visualization of protein-protein interactions in PDB at domain and amino acid resolutions

被引：234

作者：

Finn, RD ^{[1
]}

Marshall, M ^{[1
]}

Bateman, A ^{[1
]}

机构：

[1] Wellcome Trust Sanger Inst, Hinxton CB10 1SA, England

来源：

BIOINFORMATICS | 2005年 / 21卷 / 03期

关键词：

D O I：

10.1093/bioinformatics/bti011

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

There are many resources that contain information about binary interactions between proteins. However, protein interactions are defined by only a subset of residues in any protein. We have implemented a web resource that allows the investigation of protein interactions in the Protein Data Bank structures at the level of Pfam domains and amino acid residues. This detailed knowledge relies on the fact that there are a large number of multidomain proteins and protein complexes being deposited in the structure databases. The resource called iPfam is hosted within the Pfam UK website. Most resources focus on the interactions between proteins; iPfam includes these as well as interactions between domains in a single protein.

引用

页码：410 / 412

页数：3

共 13 条

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