Evaluation of a new serotyping assay for detection of anti-hepatitis C virus tvpe-specific antibodies in serum samples

被引：11

作者：

Gault, E

Soussan, P

Morice, Y

Sanders, L

Berrada, A

Rogers, B

Deny, P

机构：

[1] Univ Paris 13, Hop Avicenne, Assistance Publ Hop Paris, Lab Bacteriol Virol Hyg,EA3406,ATHSCO,UFR Sante M, F-93009 Bobigny, France

[2] Abbott Murex, Dartford DA1 5LR, England

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2003年 / 41卷 / 05期

关键词：

D O I：

10.1128/JCM.41.5.2084-2087.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The performance of a new version (HC03) of the hepatitis C virus (HCV) serotyping 1-6 assay (Abbott Murex Laboratories), a specific test for serological determination of HCV types, was evaluated using a selected panel of 180 HCV RNA-positive sera. HC03 was more sensitive than the current HC02 version, typing 53 (37.6%) of 141 samples which were not typable with HC02. Furthermore, the HC03 specificity was 94.1% as evaluated with a panel of 22 genotyped samples. This new version of the test improves the quality of the serological approach to HCV type determination.

引用

页码：2084 / 2087

页数：4

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